National Cancer Research Institute South of England
Prostate Cancer Collaborative

Links to Cancer Genome Project

The Cancer Genome Project , run by Professor Mike Stratton and Dr Richard Wooster, aims to identify cancer genes by carrying out systematic screens of human cancer for homogygous deletions (complete genetic loss), point mutations and translocations. The aim of the Collaborative is to link to this initiative by

(i) providing prostate cancer DNAs for mutational screening
(ii) to carry out Molecular Pathology studies on genes identified by the Cancer Genome Project and
(iii) to use prostate cancer genes identified in this project as targets for developing novel therapies.

This strategy is shown in the scheme below.

Collaborative Home Page

Quick Links to other pages
grey = under construction

Aetiology and Genetics

Epidemiological Identification of Families
Genetic Susceptibility
Diet and Environment

Molecular Pathology

Links to Cancer Genome Project
Development of Normal Prostate
Microarray Expression Profiling
Candidate Genes
Novel Telomerase Suppressor Genes
Subtractive Hybridization

Novel Therapies

New Drugs for Prostate Cancer
Intensity Modulated Radiotherapy
Novel Targets from Cancer Genome Project
Novel Mechanism Based Drugs

Core Resources

Cancer Gene Cloning Lab
Prostate Tissue arrays
Microarray laboratory
Tissue and blood collections

Pilot and Development Funds

Tumor micro-environment in early prostate cancer

Meetings and Seminars

Contact us on Email: Tel: 0208 643 8901 Fax: 0208 770 7290 This page last modified: 6/11/02